Take the Time for 23andMe
As I wrote in a recent short post copied below, I've had a genetic test made to find out more about my ancestry, and encourage anyone reading this to get one if you haven't already. I had a much better than average idea of my ancestry already, having read books and pamphlets about it, and the test results came back and astonished me. It did have some surprises, and weeks later, I'm still digesting the information and its' possible relevance to my future. In fact, I was inspired to get further testing done at the rival of 23andMe.com (that I used) with AncestryDNA, and 23andMe is a thousand times better. I would urge you to get your genetics test as soon as possible done at 23andMe. It's empowering to know your own genetic makeup, and know more about your health, change what you can't, manage what you can't. for your own specific body, and learn hundreds of things about your health, for only USD$99, a huge bargain at the time of this writing.
The company 23andMe was named after the 23 pairs of chromosomes within each of our cells for a total of 46. To update or possibly refresh your memory of high school biology, 22 of the pairs, called autosomes, look the same in both males and females. Females have two copies of the X chromosome in the final pair, and males have one X and one Y.
In addition to having my own genetics tested in this inexpensive test, being a writer I've composed fiction that is still in draft form and being readied for publication as a novel, that explores the topic of eugenics as one of its' themes. I've thought a lot about eugenics. For example, one of my daughters has red hair (like 4% of the world's population), green eyes (like 3% of the world's population), and B- blood, like less than 2%...Yet, is it likely or unlikely her type would have been selected by prospective parents? Oh, I found out I'm a sprinter, and I find that amusing, as everyone who has ever jogged or walked with me knows I'm not the fastest, quite the reverse, so perhaps another gene balances it out. Much is yet to be learned about genetics.
So it was with great interest that I read this opinion piece published, and presumably sanctioned, by the journal "Genetics in Medicine" the Official Journal of the American College of Medical Genetics and Genomics. It was referenced today in The Scientist Magazine linked from The Daily Beast. The controversial issue is that these scientists believe that genetics should not be hoarded by any one company, and they are disappointed that 23andMe or indeed any one particular company was given the patent.
What are parents looking for in a eugenics program? As this article says,
"The phenotypic characteristics that may be on the users’ (e.g., parents’) “shopping list” can include both disease-related and non–disease-related traits, such as height, eye color, muscle development, personality characteristics, and risks of developing age-related macular degeneration or certain types of cancer.2 Figure 4 of the patent application lists the following alternative choices: “I prefer a child with”: “longest expected life span”/“least expected life cost of health care”/“least expected cumulative duration of hospitalization...."
Also, 23andme has a competitive advantage to securing the patent if a company's going to get one. If the company's
"goal was to set a legal precedent that would keep others from profiting from any similar ‘inventions.'...
"there is no indication that this is the rationale behind the case discussed in this commentary."
My question is what was 23andMe's motivation for securing the patent?
Like other users of the site, I love what 23andMe is doing. It should be possible to conduct research with raw genomic data and advance medical science. The company has bought a crowd-sourced site that asks questions to gain insight into diseases using volunteered observations, such as whether certain pills are better for depression than exercise, or whether certain pills are better for arthritis than avoiding certain inflaming foods or exercise, and actively solicits survey rankings of popular remedies from readers.
I'm not suggesting for nanosecond that 23andMe is going in the direction of eugenics. But as this opinion piece points out, a certain amount of genetic selection is going on already, as far as the avoidance of dread diseases in offspring is concerned, whether natural or unnatural.
I have to agree: WHAT IF eugenics ran amok, and eugenically selected beings were considered superior to non-eugenically selected beings, if certain characteristics became not just desirable but mainstream and essential to professional success? The idea of eugenics being made possible by any organization or government is controversial at heart. Haven't many wars been fought about eugenics and possessiveness by cultures and nationalities?
If 23andMe is going in a certain direction why not say so? I guess since it's a private company there isn't the legal necessity, but if genes are going to direct the medicines of the future, and possibly the future of mankind, then the knowledge about them shouldn't be secretly hoarded.
In the fiction manuscript for my novel, my protagonist, a male journalist, stumbles across an illicit program and wins a major prize and a girl (instead of the scientist who was already raising her daughter)...Anyway, that's not ready for prime time yet, although my novel called Finer Spirits is finally published, a story about an alcohol poisoning, and you can read more about it here on my writer blog S J Seymour.
Since then I have tried running my results through other sites to find out diagnoses, and Promethease is one that tells you with even more details and links to the science behind raw genetic data. I didn't study genetics, but getting a test can lead in many wonderful directions and is educational. Much of it doesn't seem scary or require genetics education.
The results from general whole body genomic testing, even from the best popular site, 23andMe, should enable your doctor to tailor your medicine to what will work for you, and not for the person who happens to have an appointment before or after you. Comments on the site say doctors should be sympathetic to these tests, of else it's a sign a patient should choose another doctor. These results should help give doctors the tools they need to make accurate diagnoses and give patients the appropriate medicines and perhaps they will work harder catching up. I wish I had been able to take this information and used it years ago.
Here's one of my favorite videos about 23andMe by a doctor who understands, and has made me an unpaid cheerleader. Here's a good video about the doctor and how he incorporated the genetics test into his practice.
Here's the article referred to above, taken from an earlier post:
A month ago, I bravely ordered a gene test kit from 23andme, a company in California, and sent off a sample of my saliva. A few days ago, I received pages and pages of results that had to do with my health, and my family's health. The amount of information I received far surpassed anything I'd expected. I now have sequences of genes, some of which show my susceptibility to diseases, and I've been trying to get my family to participate, but so far have experienced notes of hostility and suspicion rather than the compliance I had hoped to gain.
Please listen to these two videos previously broadcast on American national television NBC-TV with an informative article.
And here's an article called "The ABC's of your DNA" from The New York Times to read about the current exhibit about genes at the Smithsonian in Washington, D.C., or better yet, go and see it. But at minimum, please have a gene test done.
Jobs, Money, Pride
The Best Years of Our Lives
Letter to Mrs. Assad: September 1, 2013
Internationally, Syria is known as a country headed by a despotic tyrannical dictator now being likened to Hitler, Saddam Hussein, and Mouamar Gaddafi.
In case you are unaware, it is a fact currently broadcast nationally on American television that your government has used Sarin gas. Everyone knows Sarin gas kills in ten minutes.
I can't resist writing another post imploring you to (please) exert your force and stop this tragedy in Syria. As your country's government continues to do this, you DO face international pressure to STOP.
You have already achieved international condemnation, and live in a demolished country that must be completely rebuilt.
Shame on you and your husband. I hold you two ultimately responsible.
Shelley Seymour
Had to write this after my last letters here and here.
Racism and Misogyny Exist
Book Expo America 2013
Jacob K. Javits Center, New York Cityhttp://upload.wikimedia.org/wikipedia/commons/7/76/JKJCC.JPG |
Eleventh Avenue, between 34th and 40th streets, on the West side.
Wiley had a plush carpet |
British Monarchy Expenses Should Be Transparent
More transparency of royal financial taxes and expenses would be a huge change for the better. This post explains my position, and extends a challenge.
It is.
A major issue many internationals have with the British monarchy is that the finances, rights, and powers of the monarchy remain mysterious and private.
One well-known historic right of British royalty is the right to bestow titles and elevate commoners to the aristocracy. And the Honors List is clearly one such incestuous poorly-understood system. Titles favor one person and family over others visibly for a lifetime. This bad habit promotes permanent, deeply ingrained, undemocratic social inequality. For the Honors Lists often bear scant similarity to the actual importance to society of the contributions of individuals so honored and titled. Easy for me to say this, many extremely hard-working, deserving, and worthy British scientists are repeatedly ignored by Her Majesty.
Bill Gates: Vaccinations Reduce Sickness, Improve Quality of Life, Develop Economies
The rate of childhood deaths is reduced as a direct benefit of vaccinations. And parents with fewer children tend to have more time and money to spend on each one because vaccinated children live longer. And these children tend to get more education and job opportunities. So it's a virtuous circle, a constantly re-inforced win-win outcome all round.
Gates writes that "Vaccines are the best investment to improve the human condition." And that's a weighty statement from the individual who was wealthiest person in the world for many years, and the former head of a global computer giant. And computers have infinitely improved the human condition. Bottom line: vaccinations improve business.
Boston Marathon Bystander Gives Firsthand Account
“Thank you all for your concern.
This is DK’s third Boston Marathon, and he's done others to qualify for it. I did one marathon some years back but find they take far too much time to train for. I do distances between 5K and half marathons, but walk every step - fast. I did 31 races last year, and three in February when we were in Florida.
TK (DK’s mom) and I headed back to the apartment where we’d arranged to meet him. We hadn’t walked a block when we heard a huge kaboom. We looked at each other, confused. Not thunder, since the weather was okay. A cannon in honor of the Patriots Day holiday Massachusetts was celebrating? Weird. Then another. Even more confusing. I looked back at the underpass and was astounded to see it empty, meaning the runners had been stopped: OMG, something terrible’s going on.
I tried to text DK and check the news on my phone but was worried about using up the juice too fast. So many people called and texted and emailed but the phone lines were jammed and I wanted to conserve the charge so had to make quick updates.
After that, DK headed to a place as close to the apartment as he could get. Thank goodness he was a few minutes slower than he planned. And thank goodness we didn’t find a spot to wait for him on the sidewalk outside the apartment.
We searched for DK through all the thousands of people in that big area. TK happened to gaze in a certain direction when her son appeared, ten feet away. And to our great relief, thank goodness we finally found one other.
We wandered idly along a nearby street as the police turned everyone away from the area. A lovely couple offered DK a cup of water. A hotel lobby allowed us in and we spent a little time regrouping, grateful for the warmth. But it didn’t have a television so we were getting information piecemeal. The T (subway) had been shut down as well as the Mass Ave. bridge, and it was evident we weren’t getting back into the apartment any time soon.
“It was a very intense experience...Yesterday (Monday) was remarkable. Such confusion for the ordinary person, but the police swung into action immediately and within a few minutes there were so many ambulances they stretched over blocks....We had to show our ID and keys to get back into our apartment today (Tuesday). Thank goodness the area right here is still restricted and the police/security presence is very heavy. Thank goodness our flight to Spain wasn't scheduled today...It was an experience that reminded us of the many things we're grateful for.”
Thanks go out to the writer, my sister. Have to thank her for allowing me to share it. Amazes me that family members of mine survived the attacks. Isn't it an amazing description?
Call For Action Day
Parents haven't forgotten. The entire country pledged we would do something about it after Newtown. "Shame on us if we've forgotten those kids" said President Obama. "Americans haven't moved on to other things" the President said. He says "Millions of voices" are asking for change.
My proposal is to entirely and completely banish guns from America.
Gasp if necessary, but taking away weapons of all sizes is good for society and for everyone in it who depends on peace and safety to live. America hasn't been able to wrap its' collective mind around the prospect of banning guns, although individually certain Americans agree and gun ownership in percentages supposedly has fallen in the last decades. But I just don't see any different choice that's effectively going to make a huge difference in America. And this is not a conspiracy or revolution I'm suggesting. This is just me and what I want, my attitude in favor of a minor change if you will, and my voice on this platform.
If Someone Says Rape Happened Then It Probably Did
And by the way, shame on the police for not immediately processing rape kits that they do have. It took guts for each and every woman who used one. There isn't any excuse for that on this planet.
Even if a victim doesn't report a rape and the rapist isn't punished, it doesn't mean it didn't happen. Like the article says, men should learn that it's wrong, wrong, wrong to ever rape. Because girls know in their hearts that men who rape are truly ugly trash.
Aren't Doctors Responsible for Patient Care and the Medical System?
Follow-up doesn't happen efficiently in a system where pay-per-visit insurance rules, tests are paid out of pocket in some cases, and where loyalty is uncommon as it is in America. And why should a patient be loyal if the doctor changes insurance plans, moves suddenly, and disappears after signing non-compete clauses. Doctors are also guilty of prescribing dangerous and expensive tests unnecessarily, and not advising patients of results by following through and reminding patients of another appointment. And doctors works in a system that doesn't reward loyalty and least expensive care.
Immigration: what genius glut?
Certainly, the educated should be allowed into America, and achievement should be placed above unproven potential. But at the same time, educating people for the purpose of moving them out of the country has always seemed a double-edged sword.
America Has A Gun Culture: And that's the Problem
In addition, ProPublica analyzes the lack of research with the person who was last leading the governmental effort until the gun lobby successfully stopped all gun-related research. Dr. Mark Rosenberg led gun violence research the Centers for Disease Control(CDC)'s National Center for Injury Prevention and Control in the nineties.
What he says, with unassailable logic, is scandalous:
"One of the critical studies that we supported was looking at the question of whether having a firearm in your home protects you or puts you at increased risk. This was a very important question because people who want to sell more guns say that having a gun in your home is the way to protect your family.
What the research showed was not only did having a firearm in your home not protect you, but it hugely increased the risk that someone in your family would die from a firearm homicide. It increased the risk almost 300 percent, almost three times as high.
It also showed that the risk that someone in your home would commit suicide went up. It went up five-fold if you had a gun in the home. These are huge, huge risks, and to just put that in perspective, we look at a risk that someone might get a heart attack or that they might get a certain type of cancer, and if that risk might be 20 percent greater, that may be enough to ban a certain drug or a certain product.
But in this case, we're talking about a risk not 20 percent, not 100 percent, not 200 percent, but almost 300 percent or 500 percent. These are huge, huge risks."
So to review, drugs are banned if they have a 20 percent or greater risk of maybe someday causing cancer, but guns with a 300-500 percent chance of maybe killing someone are just fine.
But Americans neither know nor care. And weapons like guns aren't totally banned. In fact, no one knows how many guns are around, or how many people die each year from guns. How can the country just turn its back on other research it has done on death and dying? Numbers don't lie! How many more lives will be lost before America gets its' act together?
Dr. Rosenberg also says that since 1996 when the gun research was disrupted, 480,000 or more deaths by murder and suicide have been estimated but not actually counted.
He calls phrases such as "obviously the assault weapon ban didn't work, because Columbine happened" kind of like saying "vaccines don't work because someone got the flu."
But of course, the real scandal is that the federal research ended and America has fallen into the vacuum of shameful ignorance. No one knows the true numbers nationwide. Neither side knows numbers for certain, especially the NRA and all those who value and use tactics of fear by spouting slogans and false statistics rather than knowledge.
The least that can be done is to pass gun bans on large weapons and background checks, but that's not stopping sales of casual weapons.
NPR said there isn't a national registry for such deaths. No one knows which weapons were used or how many people have died in this internal civil war.
Americans need to get rid of problem legislation such as this:
"In 2003, Rep. Todd Tiahrt, a Republican from Kansas, added language to the Justice Department's annual spending bill. It says the Bureau of Alcohol, Tobacco, Firearms and Explosives can't release information used to trace guns involved in crime to researchers and members of the public. It also requires the FBI to destroy records on people approved to buy guns within 24 hours."
To review, gun tracing and gun-approval information can't be done by law. But without real actual knowledge, nothing's going to improve for America, as far as gun violence is concerned. The mental health alleyway is bogus and going nowhere because it limits the actions of those who would restrict gun sales to those who judge someone else is crazy. And those mental health judges are possibly going to become instant targets by rejecting any gun application, and have to be separated from the process. The process should be impersonal.
The President of the National Rifle Association (NRA) called the following tenets official policy of the organization on the radio (NPR) here. Pres. Keene thinks it's not good to restrict weapons because:
1) Banning assault weapons is not going to stop the real mass killers.
(As opposed to what, may I ask--serial killers or someone who just wants to shoot just one person?) This is silly. He has no evidence or research to support this because none has been done by anyone, officially or unofficially. For proof, please read ProPublica.
2) America with no guns would be total chaos and anarchy.
Honestly, it sounds to me like anyone saying this is a bit off their rocker, just a bit! What are they talking about? Crazy! How absurd the idea! America needs fewer guns not more. Not having guns, even less than not smoking, isn't going to stop mothers from feeding their newborns.
And incidentally the President of the NRA's command of the English language wasn't very coherent in this interview, but he was sly, persuasive, and crazy like a fox!
3) Gun registries lead to gun confiscation by the government and to possible publication of gun ownership.
Kind of an odd worry considering more than half of gun owners buy or obtain them illegally and keep them in secret. But pity them, there isn't any knowledge to go around from one side to the other. The gun lobby especially is lurching around with blind accusations and slogans that sound rational on the outside rather than obtaining hard facts and numbers. And (the bastards like Keene at) the NRA have successfully stopped such genuine research into gun deaths and arguments in the past. (How? With techniques that include minimizing counter-arguments and using intimidating threats that keep political opponents out of office.)
4) "That's not much." The prodigious ammunition reserves of the Aurora shooter wasn't so large. "You can use up a lot of ammunition in sport and competitive shooting."
Until guns are totally banned, I believe the numbers won't improve in favor of saving lives, although every little bit of good legislation helps. America will continue to be a violent gun culture at heart. And that's a problem for others even if it's not recognized as such. America won't admit to an addiction problem to guns. They say Mexicans and other countries have more gun violence. But like avoiding another car on a slippery road in winter, Americans can't see the outside picture and the possibilities, and how much trouble they could conceivably cause other countries. America can fight the addiction, but they still need to take real action and catch up to other peaceful cultures as far as guns are concerned. It's past time.
Can British Royalty Honestly Expect Privacy Abroad?
This mischievous behavior isn't something the Queen of England has ever done. One would think she should be more disappointed with her son's wife than with the press recording an event. But pregnancy doesn't last long, and the beautiful Princess didn't learn her lesson in France last summer on the topic of "assumption of privacy." If she's going to be out and about in public, she's likely to be photographed, she evidently might be even where she assumes it's private.
The press is certainly making the issue balloon larger, but it's good for publicity in the business of entertainment. The names of the magazines involved in these photos, for example, were previously unknown to me, and probably most Americans.
Is America Imploding? NRA Lists Enemies
The NRA "works" by scaring the general population with slogans, that Americans need more guns for self-defense, and that they have a right to any gun they want. Scaring Americans furthers the aims of the NRA to sell more guns. Strangely enough, they believe that by gathering names of businesses and celebrities who aren't helping them, they're winning as a public relations organization! Sounds like when Hitler published the names of Jews he didn't like in the Second World War. And we all know how wrong he proved in history.
The bombs of WWII killed many more than that in Japan.
3) Guns are useful for self-defense because there's supposedly the constitutional right to bear arms.
Surely there are other more rational methods of self-defense (classes in self-defense spring to mind). By the time Americans have to resort to the use of firearms, it means that all other vestiges of civil society, including conversation, have failed. And as for constitutional rights, certain sensible and experienced legal scholars want to limit or dispose of that idea.
Here's the NRA list of over 500 names. Here's scholarly opinion on limiting the Second Amendment, and more recently here and here.
Violence Control: The Wider American Problem
1) Can violent video games be regulated?
2) And didn't shooting sprees happen before video games were invented?
UPDATE: Another fascinating statistic comes from an article in the New York Times:
"According to the Centers for Disease Control and Prevention, 38,364 Americans lost that fight in 2010 and committed suicide; 19,392 used a gun."